Dr. Esmaeil Zadeh has established a line of research at the intersection of information systems and health informatics, focusing on the impact of health information technology (HIT) and emerging technologies on the performance of health systems, improving the quality and efficiency of care delivery and enhancing the engagement of patients in managing their care. His main research objective is to study various HIT systems to offer technological solutions for enhancing health information exchange (HIE) across providers, care coordination, healthcare providers’ workflows, system security, patient safety, the completeness and accuracy of medical records, and healthcare interoperability standards. He is also interested in other research domains, including Nonfungible Tokens (NFTs), blockchain-based platforms, Artificial Intelligence (AI) and Machine Learning (ML), Robotics, Health app development, and Metaverse. His work appears in premier Information Systems and Health Informatics journals such as Information and Management, International Journal of Medical Informatics, Journal of Medical Internet Research, Journal of Biomedical Informatics, BMC Medical Informatics and Decision Making, Communications of the Association for Information Systems, Computers and Security, Information Technology & People, and Methods of Information in Medicine. He was appointed to a Knight-Ridder Center Research Fellowship in August 2021. He also received the Fulbright Award from the Canada-US Fulbright Program for the 2022-2023 academic year.